Assessment of impaired fasting glucose in obese and overweight insulin-resistant children by continuous glucose monitoring.

Corresponding Author: Zoltan Antal, M.D., 525 E. 68th St., Box 103, New York, NY 10065; email address [email protected] The childhood obesity epidemic has been accompanied by an increase in the prevalence of type 2 diabetes mellitus, with impaired glucose tolerance (IGT) reported in 10–27% of obese children and adolescents across the globe.1,2 The natural history of impaired fasting glucose (IFG) and IGT is variable, with ~25% progressing to diabetes, 50% remaining in their abnormal glycemic state, and 25% reverting to normal glucose tolerance over an observational period of 3–5 years.3